The 4DCellFate network consists of+ Read more
11 European partner institutions (with 13 scientific laboratories), 2 SMEs, and a large pharma company
with scientific expertise in proteomics, structural biology, biochemistry, and cell biology tackling some of the most relevant questions of epigenetics and cell fate.
We started 1.12.2011 and will run for 5 years.
Nature: TFIID structure+ Read more
In a highly collaborative approach, the teams of Berger, Schaffitzel, P. Schultz and L. Tora have described in molecular detail the architecture of the human core TFIID complex, as published recently in Nature.
Central to this breakthrough was their innovative method for producing high-quality, correctly-assembled multi-protein complexes.
EpiGeneSys_4DCellFate workshop: Epigenetics in Cancer+ Read more
Joint EpiGeneSys/4DCellFate student and post-doc workshop
A workshop organized by the students and post-docs of the EpiGeneSys training advisory board, and co-sponsered by 4DCellFate, will be held at the CRG in Barcelona, Spain. Participants from the EU projects EpiGeneSys and 4DCellFate will attend a series of lectures from top scientists in the fields and network over lunches, dinners, and smaller sessions with the speakers.
The 4DCellFate project aims to elucidate how the PRC and NuRD complexes control cell fate, by systematically analyzing various aspects of these complexes: their structure, their function in various cellular contexts, and their interactions with other regulatory factors, nucleic acids, and nucleosomes.
4DCellFate is a project in the 'Health Theme' of the European Commission's Seventh Framework Programme, with the grant agreement no. 277899.